Contact Us

Emil R. Unanue
unanue@wustl.edu

Physical Location
Barnes Jewish Children's Institute for Health, 8th Floor

Office Phone
(314) 747-0561 

Mailing Address
Washington University School of Medicine
Department of Pathology and Immunology
660 S. Euclid Avenue, Campus Box 8118
St. Louis, MO 63110 USA

The techniques used in the laboratory are available by writing to us at: unanue@wustl.edu. These include MHC-class II isolation, peptide-MHC binding, T cell assays, hybridoma development, peptide analysis, radioiodination, peptide isolation from MHC molecules, islet isolation and examination, and others.

Most of the strains of mice that we use are available at the Jackson laboratory. We presently mainly use the NOD diabetic mouse strain as well as variants of it.

T cells to insulin peptides in form of hybridomas are available upon request. Two TCR transgenic mice to insulin peptides are also available.

From our early studies on antigen processing, T cell hybridomas to various HEL and insulin peptides can be obtained by contacting us at our email address. Also the B cell hybridoma producing antibodies to the 48-61 peptide of hen-egg white lysozyme bound to I-Ak is available at ATCC: AW 3.18.14: ATCC number CRL-2826. The B cell hybridoma producing an antibody specific to the 3A9 clonotype (a T cell reactive to 48-61-I-Ak complex) is available at ATCC:
IG12: ATCC number CRL-2827

Our laboratory is supported by grants from:

The NIH; in particular, the National Institute of Allergy and Infectious Diseases; the National Institure of Diabetes and Digestive Diseases.

Janssen Pharmaceuticals, a subsidiary of Johnson and Johnson.

The Kilo Diabetes and Vascular Research Foundation. 

Last revision: July 2018

Graduate Program Affiliation: Immunology Program